Curriculum Coverage
Biochemistry
• Definition of glycolysis
• Glucose transport via GLUT transporters
• Reactions of glycolysis
• NADH shuttle systems
• Energetics of glycolysis
• Fate of pyruvate
• Types of glycolysis
• Anaerobic glycolysis
• Key enzymes of glycolysis
• Regulation of glycolysis
• Glycolysis in RBC
• Glycolysis in cancer cells
• Clinical disorders of glycolysis
• Conversion of pyruvate into acetyl CoA
• Enzymes of PDH complex
• Coenzymes of PDH complex
• Reaction sequence of PDH complex
• Regulation of PDH
• Clinical aspects of PDH deficiency
• Definition of gluconeogenesis
• Organs of gluconeogenesis
• Cellular location
• Substrates of gluconeogenesis
• Three bypass reactions
• Gluconeogenesis from fatty acids
• Cori cycle
• Regulation of gluconeogenesis
• Key enzymes of gluconeogenesis
