Topic 33 – Hexose Monophosphate Shunt (Pentose Phosphate Pathway)

Focuses on NADPH production and antioxidant defense.

Curriculum Coverage

Biochemistry

• Role of pentose phosphate pathway

• Tissues where HMP shunt occurs

• Reactions of oxidative phase

• Reactions of non-oxidative phase

• Role of thiamine

• Similarities and differences between glycolysis and HMP pathway

• Functions of NADPH

• G6PD deficiency

• Regulation of HMP pathway

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