This topic integrates ketone metabolism and complex lipid synthesis pathways.
Curriculum Coverage
Biochemistry
Ketone Body Metabolism
• Ketone bodies
• Definition of ketogenesis
• Steps of ketogenesis
• Energy yield during ketogenesis
• Conditions causing increased ketogenesis
• Utilization of ketone bodies
• Energy yield of ketone utilization
• Regulation of ketogenesis
• Ketoacidosis in diabetes
Complex Lipid Metabolism
• Synthesis of triacylglycerol
• Synthesis of phosphatidic acid
• Substances formed from phosphatidic acid
• Synthesis of glycerophospholipids
• Degradation of glycerophospholipids
• Synthesis of ceramide
• Synthesis of sphingomyelin
• Degradation of sphingomyelin
• Niemann-Pick disease
• Farber disease
• Synthesis of glycosphingolipids
• Degradation of glycosphingolipids
• Abnormalities of phospholipid metabolism