📘 Step 1. Curriculum Coverage

🔬 Pathology

• Gastritis: types, etiology, microscopic morphology and clinical features.
• Peptic ulcer disease: etiology, pathophysiology, morphology, complications and laboratory diagnosis.
• Role of H. pylori and Campylobacter in peptic ulcer disease.
• H. pylori and Campylobacter: morphology, virulence factors and laboratory diagnosis.

💊 Pharmacology

• Classification of drugs used in peptic ulcer disease.
• PPIs: mechanism, indications, adverse effects, pharmacokinetics and timing of administration.
• Omeprazole and H2-blocker interactions with sucralfate; omeprazole–clopidogrel interaction.
• H2 blockers: mechanism, indications, adverse effects, bioavailability and drug interactions.
• Antacids: mechanism, indications, adverse effects, ideal properties, pharmacokinetics and interactions with tetracyclines, iron and fluoroquinolones.
• Sucralfate: mechanism, indications, pharmacokinetics and interactions with digoxin, ketoconazole and tetracyclines.
• Bismuth compounds: mechanism, indications and adverse effects.
• Anticholinergic drugs in peptic ulcer disease: role and indications.
• Misoprostol: pharmacological basis and contraindications.
• Triple and quadruple therapy for H. pylori eradication.

🩺 Medicine

• Gastritis: types, etiology, clinical features, investigations, management and complications.
• Peptic ulcer disease: types, etiology, clinical features, investigations, management and complications.
• H. pylori eradication protocols.