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GIT & Hepatobiliary-II Module — 4th Year MBBS

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KMU Past Paper Practice

Oropharyngeal, Salivary Gland and Upper Aerodigestive Disorders

4th Year MBBS • 20 A-type Single Best Answer MCQs

MCQ 1

Question:

A 23-year-old woman has recurrent painful oral ulcers that interfere with eating. Examination shows shallow ulcers on non-keratinized mucosa with no induration, and investigation reveals no systemic disease. Which management is most appropriate to reduce local inflammation?

Options:

Systemic antibacterial therapy
Surgical excision of each lesion
Topical corticosteroid therapy
Antiviral therapy for herpes infection
Immediate neck imaging
Correct Answer:
Topical corticosteroid therapy
Explanation: Topical corticosteroids reduce local inflammation in recurrent aphthous ulcers when no correctable underlying cause is identified.

MCQ 2

Question:

A 58-year-old man has a solitary oral ulcer that has persisted for several weeks despite removal of local irritants. It has irregular margins and feels firm at its base. Which investigation is most appropriate?

Options:

Biopsy of the lesion
Pure-tone audiometry
Serum amylase measurement
Routine chest radiography
Salivary duct imaging
Correct Answer:
Biopsy of the lesion
Explanation: A persistent, atypical or indurated oral ulcer requires tissue assessment because a simple recurrent aphthous ulcer should not remain persistently indurated.

MCQ 3

Question:

A newborn with an unrepaired cleft palate has difficulty maintaining suction and milk repeatedly escapes through the nose. The infant is otherwise stable. Which immediate management principle is most appropriate?

Options:

Begin antibiotic prophylaxis
Perform urgent tonsillectomy
Arrange immediate hearing-aid fitting
Start long-term steroid therapy
Provide feeding and nutritional support
Correct Answer:
Provide feeding and nutritional support
Explanation: Early management of cleft palate focuses on safe feeding and adequate nutrition before definitive surgical repair and later functional rehabilitation.

MCQ 4

Question:

A school-age child with repaired cleft lip and palate develops abnormal dental alignment and malocclusion. Which component of long-term multidisciplinary care is most relevant to this complication?

Options:

Neurological rehabilitation
Dental and orthodontic assessment
Endocrine evaluation
Renal imaging
Gastrointestinal endoscopy
Correct Answer:
Dental and orthodontic assessment
Explanation: Clefts involving the alveolar and maxillary region can disturb tooth eruption and occlusion, making dental and orthodontic follow-up important.

MCQ 5

Question:

A 15-year-old boy recovers from an episode of febrile exudative tonsillitis caused by group A streptococci. Two weeks later, he develops migratory joint pains. Which recognized consequence of the original infection best explains the new illness?

Options:

Direct bacterial invasion of the joints
Salivary duct obstruction
Peritonsillar fibrosis
Post-infectious immune-mediated disease
Viral superinfection of the pharynx
Correct Answer:
Post-infectious immune-mediated disease
Explanation: Acute rheumatic fever is an immune-mediated complication following group A streptococcal pharyngeal infection rather than direct bacterial invasion of tissues.

MCQ 6

Question:

A 17-year-old student presents with acute sore throat, fever and tonsillar exudate. The clinical findings do not clearly distinguish a viral from bacterial cause, and the result would alter treatment. Which investigation is most useful?

Options:

Throat microbiological testing
Parotid ultrasonography
Barium swallow examination
Audiometric evaluation
Cervical spine radiography
Correct Answer:
Throat microbiological testing
Explanation: Microbiological testing is appropriate when confirmation of a bacterial cause will influence whether antibacterial treatment is required.

MCQ 7

Question:

A 29-year-old man has a long history of recurrent tonsillar inflammation. Examination between attacks reveals relatively small, firm tonsils rather than hypertrophied tonsils or crypts filled with debris. Which form of chronic tonsillitis best explains this appearance?

Options:

Chronic follicular tonsillitis
Chronic parenchymatous tonsillitis
Chronic fibroid tonsillitis
Acute bacterial tonsillitis
Peritonsillar cellulitis
Correct Answer:
Chronic fibroid tonsillitis
Explanation: Repeated inflammation may lead to fibrosis, producing relatively small, firm tonsils characteristic of the fibroid form of chronic tonsillitis.

MCQ 8

Question:

A young adult with a peritonsillar collection speaks with a muffled quality despite normal vocal-cord function. Which local change best explains the altered voice?

Options:

Parotid duct obstruction
Facial nerve weakness
Middle-ear effusion
Palatal congenital defect
Oropharyngeal soft-tissue swelling
Correct Answer:
Oropharyngeal soft-tissue swelling
Explanation: Peritonsillar swelling alters the resonating space of the oropharynx and produces the characteristic muffled quality of speech.

MCQ 9

Question:

A 12-year-old boy develops fever and painful bilateral parotid swelling. There is no purulent discharge from Stensen duct and no focal abscess. Which treatment approach is most appropriate?

Options:

Immediate gland excision
Hydration, analgesia and supportive care
Drainage of the parotid duct
Long-term antibacterial prophylaxis
Radiotherapy to the gland
Correct Answer:
Hydration, analgesia and supportive care
Explanation: The presentation is consistent with uncomplicated viral parotitis, for which management is mainly supportive rather than antibacterial or surgical.

MCQ 10

Question:

A patient presents with a persistent painless lump in the parotid region without fever, meal-related pain or duct discharge. Which broad category of salivary-gland disease should be considered most strongly?

Options:

Acute inflammatory disease
Obstructive duct disease
Acute viral disease
Neoplastic disease
Suppurative duct infection
Correct Answer:
Neoplastic disease
Explanation: A persistent painless salivary-gland mass without inflammatory or obstructive features raises concern for a salivary neoplasm.

MCQ 11

Question:

A 40-year-old man has symptoms suggesting submandibular duct obstruction. On examination, a stone is not clearly palpable. Which investigation may demonstrate a calculus when it contains sufficient mineral to be radiopaque?

Options:

Magnetic resonance angiography
Plain radiography
Pure-tone audiometry
Barium swallow
Electroencephalography
Correct Answer:
Plain radiography
Explanation: A sufficiently radiopaque salivary calculus can be visualized on plain radiography, although other imaging may be needed for non-visible stones.

MCQ 12

Question:

A patient has mild intermittent salivary duct obstruction without fever, abscess or severe gland damage. Which initial conservative measure is most appropriate?

Options:

Immediate total gland removal
Chemoradiotherapy
Topical oral corticosteroids
Elective tonsillectomy
Hydration, salivary stimulation and massage
Correct Answer:
Hydration, salivary stimulation and massage
Explanation: Minor uncomplicated obstruction may improve by increasing salivary flow and encouraging passage of obstructive material before invasive treatment is considered.

MCQ 13

Question:

A woman has had a slowly enlarging painless parotid mass for many years. Histology confirms pleomorphic adenoma. Why is prolonged persistence of this lesion clinically important?

Options:

There is a risk of malignant transformation
It invariably produces bacterial parotitis
It commonly causes bilateral gland enlargement
It characteristically obstructs the submandibular duct
It routinely causes acute tonsillitis
Correct Answer:
There is a risk of malignant transformation
Explanation: Long-standing pleomorphic adenoma is clinically important because malignant transformation can occur in a lesion that has persisted for a prolonged period.

MCQ 14

Question:

A 64-year-old patient has a rapidly enlarging salivary-gland mass that has become fixed to surrounding tissues. Which interpretation is most appropriate?

Options:

The lesion is most consistent with uncomplicated mumps
The findings favor simple duct obstruction
The findings raise concern for malignant behavior
The findings are typical of an aphthous ulcer
The lesion represents chronic tonsillar fibrosis
Correct Answer:
The findings raise concern for malignant behavior
Explanation: Rapid growth and fixation suggest invasion of surrounding tissues and are concerning clinical features in a salivary-gland mass.

MCQ 15

Question:

A salivary-gland carcinoma shows predominantly solid areas, increased cellular atypia and destructive growth rather than prominent cystic spaces. Which interpretation best fits these findings?

Options:

Benign pleomorphic adenoma
Warthin tumor
Chronic obstructive sialadenitis
Higher-grade mucoepidermoid carcinoma
Viral parotitis
Correct Answer:
Higher-grade mucoepidermoid carcinoma
Explanation: Higher-grade mucoepidermoid carcinomas tend to be more solid, atypical and destructive, whereas lower-grade lesions contain more cystic and mucus-producing areas.

MCQ 16

Question:

Gross examination of a parotid tumor shows a well-circumscribed mass with prominent cystic spaces. Microscopy demonstrates oncocytic epithelium supported by lymphoid tissue. Which gross-pathological correlation is most appropriate?

Options:

The cystic appearance is compatible with Warthin tumor
The appearance indicates chronic bacterial abscess
The appearance is characteristic of sialolithiasis
The lesion represents chronic tonsillar disease
The finding indicates aphthous ulceration
Correct Answer:
The cystic appearance is compatible with Warthin tumor
Explanation: Warthin tumor is commonly well circumscribed and may be cystic, correlating with its papillary-cystic oncocytic histology and lymphoid stroma.

MCQ 17

Question:

A patient has progressive throat discomfort, dysphagia and a lesion suspected to arise from the posterior oropharynx, but the area cannot be fully inspected through the mouth. Which assessment is most appropriate for direct visualization?

Options:

Pure-tone audiometry
Salivary duct massage
Plain abdominal radiography
Serum amylase testing
Endoscopic examination
Correct Answer:
Endoscopic examination
Explanation: Endoscopy allows direct assessment of upper aerodigestive sites that are not adequately visualized during routine oral examination.

MCQ 18

Question:

A biopsy confirms squamous cell carcinoma of the tonsillar region. The clinician now needs to evaluate deep local extension and cervical lymph-node involvement. Which investigation is most appropriate?

Options:

Throat swab culture
CT or MRI of the relevant region
Tympanometry
Dental panoramic radiography alone
Serum vitamin B12 level
Correct Answer:
CT or MRI of the relevant region
Explanation: Cross-sectional imaging is used to assess the extent of the primary lesion, deeper tissue involvement and regional cervical nodes.

MCQ 19

Question:

A patient with an oropharyngeal mass undergoes complete head-and-neck examination. Why is systematic palpation of the cervical lymph-node regions an essential part of this assessment?

Options:

It confirms viral parotitis
It identifies salivary duct stones
It assesses Eustachian tube function
It evaluates possible regional metastatic disease
It determines salivary flow rate
Correct Answer:
It evaluates possible regional metastatic disease
Explanation: Oropharyngeal cancers can involve cervical lymph nodes, so careful neck examination contributes directly to clinical assessment of regional disease.

MCQ 20

Question:

A 57-year-old patient has a localized oropharyngeal squamous cell carcinoma without airway compromise. During counseling, the patient asks about the broad curative treatment approaches that may be used depending on site and disease extent. Which response is most appropriate?

Options:

Long-term antibacterial therapy alone
Repeated incision and drainage
Surgery, radiotherapy or combined oncological treatment
Topical oral corticosteroids alone
Salivary gland massage and hydration
Correct Answer:
Surgery, radiotherapy or combined oncological treatment
Explanation: Curative management of oropharyngeal carcinoma depends on site and extent and may involve surgery, radiotherapy or combined oncological treatment.
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