Course Content
Blood & Immunology Module — 3rd Year MBBS

📘Step 1. Curriculum Coverage

🔬 Pathology

 

General Approach to Anemia

  • Discuss the physiological basis of anemia.
  • Classify anemias according to the underlying mechanism.
  • Describe the pathogenesis of blood-loss anemia.

Iron-Deficiency Anemia

  • Discuss the pathophysiological mechanism of iron-deficiency anemia.
  • Describe its clinical course and morphological changes.
  • Explain the laboratory investigations used for diagnosis.

Megaloblastic Anemia

  • Describe megaloblastic anemia.
  • Explain its pathogenesis with reference to vitamin B12 and folic-acid deficiency.
  • Discuss morphological changes involving RBCs, WBCs and platelets.
  • Explain the diagnostic approach to determining the underlying cause.

Aplastic Anemia

  • Enumerate the causes of aplastic anemia.
  • Describe its pathophysiology.
  • Explain the diagnostic approach to aplastic anemia.

💊 Pharmacology

 

Drugs Used in Anemia

  • Classify drugs used in anemia.
  • Describe the pharmacokinetics of iron.
  • Describe oral and parenteral iron preparations.
  • Describe adverse effects of iron therapy.
  • Describe treatment of iron toxicity.
  • Describe oral and parenteral preparations of cyanocobalamin.
  • Describe the clinical uses of vitamin B12.
  • Describe the clinical uses of folic acid.
  • Explain the pharmacological rationale for combining cyanocobalamin, folic acid and iron.

🌍 Community Medicine

 

Nutritional Anemia in Pakistan

  • Classify nutritional anemias.
  • Describe populations at risk of nutritional anemia in Pakistan.
  • Describe risk factors for nutritional anemias.
  • Describe the most prevalent anemias affecting the population of Pakistan and identify vulnerable populations and their risk factors.
  • Explain effective public-health strategies for prevention of nutritional anemias in Pakistan.

🔁 Basic Science Spiral Link

 

Erythropoiesis and Red Cell Indices

  • Discuss the steps of erythropoiesis.
  • Correlate erythropoiesis with red cell indices and their clinical implications.

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