Course Content
Blood & Immunology Module — 3rd Year MBBS

📘Step 1. Curriculum Coverage

🔬 Pathology

 

Hereditary Spherocytosis

  • Discuss the pathogenesis of hereditary spherocytosis.
  • Describe the characteristic morphological changes.
  • Explain the diagnostic approach.

Sickle Cell Anemia

  • Describe the etiology and pathogenesis of sickle cell anemia.
  • Describe RBC morphology in sickle cell anemia.
  • Explain the diagnostic approach.

Thalassemia

  • Describe thalassemia.
  • Discuss factors contributing to the pathogenesis of β-thalassemia.
  • Explain the genetics of thalassemia.
  • Describe the morphological changes, including peripheral blood findings.
  • Explain the diagnosis of α- and β-thalassemia.

G6PD Deficiency

  • Classify G6PD deficiency.
  • Discuss its pathogenesis with reference to oxidative injury to RBCs.
  • Describe characteristic RBC morphology.
  • Explain the diagnostic approach.

Paroxysmal Nocturnal Hemoglobinuria

  • Describe the pathophysiology of PNH.
  • Explain its diagnosis.

Immune Hemolytic Anemias

  • Classify immune hemolytic anemias.
  • Discuss the mechanisms of warm- and cold-antibody immune hemolysis.
  • Explain the diagnostic workup of immune hemolytic anemia.

🩺 Medicine

 

  • Discuss investigations.andmanagement principles of sickle cell anemia

👶 Pediatrics

 

Thalassemia

  • Describe the classification of thalassemia.
  • Discuss laboratory investigations.
  • Describe principles of management of thalassemia.

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