📘Step 1. Curriculum Coverage
🔬 Pathology
Hereditary Spherocytosis
- Discuss the pathogenesis of hereditary spherocytosis.
- Describe the characteristic morphological changes.
- Explain the diagnostic approach.
Sickle Cell Anemia
- Describe the etiology and pathogenesis of sickle cell anemia.
- Describe RBC morphology in sickle cell anemia.
- Explain the diagnostic approach.
Thalassemia
- Describe thalassemia.
- Discuss factors contributing to the pathogenesis of β-thalassemia.
- Explain the genetics of thalassemia.
- Describe the morphological changes, including peripheral blood findings.
- Explain the diagnosis of α- and β-thalassemia.
G6PD Deficiency
- Classify G6PD deficiency.
- Discuss its pathogenesis with reference to oxidative injury to RBCs.
- Describe characteristic RBC morphology.
- Explain the diagnostic approach.
Paroxysmal Nocturnal Hemoglobinuria
- Describe the pathophysiology of PNH.
- Explain its diagnosis.
Immune Hemolytic Anemias
- Classify immune hemolytic anemias.
- Discuss the mechanisms of warm- and cold-antibody immune hemolysis.
- Explain the diagnostic workup of immune hemolytic anemia.
🩺 Medicine
- Discuss investigations.andmanagement principles of sickle cell anemia
👶 Pediatrics
Thalassemia
- Describe the classification of thalassemia.
- Discuss laboratory investigations.
- Describe principles of management of thalassemia.
