📘Step 1. Curriculum Coverage
🔬 Pathology / Immunology
Innate and Adaptive Immunity
- Describe the functions and types of immunity.
- Enlist the three lines of defense and describe their properties.
- Describe the origin, characteristics and functions of cells of the immune system.
- Compare innate and acquired immunity.
- Compare active and passive immunity.
Humoral Immunity
- Describe the roles of T and B lymphocytes in immunity.
- Describe the role of B lymphocytes in humoral immunity.
- Explain humoral immune responses.
- Explain how helper T cells regulate immune responses.
- Differentiate humoral and cell-mediated immunity.
Cell-Mediated Immunity
- Explain specificity of the immune response.
- Describe cellular components involved in CMI.
- Explain the major cell types involved.
- Illustrate the schematic representation of T-cell activation and diversity.
- Differentiate primary and secondary immune responses.
Antigens and Antibodies
- Describe antigens and antibodies.
- Differentiate monoclonal and polyclonal antibodies.
- Classify immunoglobulins.
- Illustrate and describe the structure of immunoglobulin A
- Describe important functions of immunoglobulins.
- Explain antibody-mediated neutralization of toxins, microbes and viruses.
- Explain immunoglobulin class switching.
- Explain transfer of maternal immunity to the fetus and breast-fed infant.
Complement System
- Describe the complement system and its components.
- Describe synthesis of complement proteins.
- Explain complement activation and inactivation pathways.
- Describe the important functions of complement components.
- Describe diseases associated with complement-protein deficiencies.