Course Content
Ophthalmology (Eye) Module β€” 4th Year MBBS
AIM β€’ KMU EXAM PRACTICE

KMU Past Paper Practice

Topic 7 β€” Uveitis: Classification, Evaluation & Management

4th Year MBBS β€’ Ophthalmology β€’ 20 A-type Single Best Answer MCQs

MCQ 1

Question:

A 26-year-old woman reports blurred vision and several moving shadows. Examination shows that inflammation is centered predominantly within the vitreous and peripheral retinal-ciliary region, with little anterior chamber activity. How should this uveitis be classified?

Options:

Anterior uveitis
Posterior uveitis
Panuveitis
Intermediate uveitis
Iridocyclitis
Correct Answer: Intermediate uveitis
Explanation: Intermediate uveitis is centered mainly in the vitreous and peripheral retina/ciliary body region rather than the anterior chamber or choroid.

MCQ 2

Question:

A 30-year-old man has experienced three separate attacks of ocular inflammation over two years, with complete clinical inactivity between episodes. Which description best characterizes the course of his disease?

Options:

Chronic uveitis
Recurrent uveitis
Panuveitis
Intermediate uveitis
Granulomatous uveitis
Correct Answer: Recurrent uveitis
Explanation: Recurrent disease presents as repeated inflammatory episodes separated by periods of inactivity rather than continuously persistent inflammation.

MCQ 3

Question:

A 28-year-old patient presents with episodes of blurred vision and posterior ocular inflammation. Further history reveals repeated painful oral ulcers and recurrent genital ulceration. Which systemic disorder should be considered most strongly?

Options:

Ankylosing spondylitis
Sarcoidosis
Juvenile idiopathic arthritis
Herpes zoster ophthalmicus
BehΓ§et disease
Correct Answer: BehΓ§et disease
Explanation: The combination of recurrent oral and genital ulceration with intraocular inflammation is an important clinical pattern suggesting BehΓ§et disease.

MCQ 4

Question:

An 11-year-old girl receiving follow-up for chronic inflammatory arthritis is found to have anterior chamber inflammation during an ophthalmic assessment. Which systemic association is most relevant to this presentation?

Options:

Juvenile idiopathic arthritis
BehΓ§et disease
Tuberculosis
Syphilis
Toxoplasmosis
Correct Answer: Juvenile idiopathic arthritis
Explanation: Juvenile idiopathic arthritis is an important systemic association of anterior uveitis in children and should be recognized in this clinical setting.

MCQ 5

Question:

A 23-year-old man develops ocular pain, photophobia and anterior chamber inflammation several days after a blunt injury to the eye. Which etiological category best explains the inflammatory episode?

Options:

Autoimmune retinal disease
Herpetic ocular infection
Ocular trauma
Systemic granulomatous disease
Retinal vascular occlusion
Correct Answer: Ocular trauma
Explanation: Trauma can disrupt intraocular tissues and trigger anterior uveal inflammation, so the temporal relation to eye injury is diagnostically important.

MCQ 6

Question:

During slit-lamp examination of a patient with anterior uveitis, multiple inflammatory deposits are seen on the posterior surface of the cornea. On which structure are these deposits located?

Options:

Corneal epithelium
Corneal endothelium
Anterior lens capsule
Posterior lens capsule
Retinal pigment epithelium
Correct Answer: Corneal endothelium
Explanation: Keratic precipitates are collections of inflammatory cells deposited on the corneal endothelium during anterior uveal inflammation.

MCQ 7

Question:

A patient with acute anterior uveitis has a painful red eye and a relatively small pupil before treatment. Which mechanism best accounts for the pupillary finding?

Options:

Paralysis of the iris sphincter
Loss of retinal photoreceptors
Compression of the optic nerve
Spasm of the inflamed iris sphincter
Weakness of the ciliary zonules
Correct Answer: Spasm of the inflamed iris sphincter
Explanation: Acute iris inflammation promotes sphincter spasm, producing the characteristic relatively miotic pupil seen in anterior uveitis.

MCQ 8

Question:

A 35-year-old man with acute anterior uveal inflammation has a deep violaceous-red flush concentrated around the corneal limbus. Which vascular change best explains this appearance?

Options:

Dilatation of retinal arteries
Obstruction of choroidal veins
Constriction of conjunctival vessels
Occlusion of the central retinal artery
Congestion of the anterior ciliary circulation
Correct Answer: Congestion of the anterior ciliary circulation
Explanation: Inflammation of the anterior uveal tract congests deeper anterior ciliary vessels, producing the characteristic circumcorneal or ciliary flush.

MCQ 9

Question:

Fundus examination of a patient with posterior uveitis demonstrates an inflammatory lesion arising primarily from the vascular layer beneath the retina. The overlying retina is not the main site of inflammation. Which term best describes the lesion?

Options:

Choroiditis
Retinitis
Iritis
Keratitis
Cyclitis
Correct Answer: Choroiditis
Explanation: Choroiditis describes inflammation centered in the choroid, whereas retinitis is primarily retinal and chorioretinitis involves both tissues.

MCQ 10

Question:

A patient with posterior ocular inflammation notices a new localized dark area in the visual field. The cornea, anterior chamber and lens are clear. Which anatomical disturbance most directly accounts for this symptom?

Options:

Iris sphincter dysfunction
Corneal endothelial dysfunction
Focal retinal involvement
Ciliary muscle dysfunction
Lens capsular fibrosis
Correct Answer: Focal retinal involvement
Explanation: Localized retinal inflammation can disturb function in a specific retinal region and produce a corresponding scotoma or area of visual distortion.

MCQ 11

Question:

A 39-year-old patient with granulomatous intraocular inflammation reports prolonged cough and close household contact with a patient treated for pulmonary tuberculosis. Which investigation strategy is most appropriate?

Options:

Thyroid-function assessment
Renal-function assessment
Audiological assessment
Tuberculosis-directed assessment
Pancreatic-enzyme assessment
Correct Answer: Tuberculosis-directed assessment
Explanation: Compatible ocular inflammation plus respiratory symptoms and significant exposure justify targeted evaluation for tuberculosis rather than unrelated screening tests.

MCQ 12

Question:

A patient appears to have anterior uveitis on slit-lamp examination, but the reduction in visual acuity seems greater than expected from the anterior findings. Which examination should be performed to ensure significant posterior involvement has not been missed?

Options:

Schirmer testing
Dilated fundus examination
Corneal pachymetry
Tear-film assessment
Extraocular-movement testing
Correct Answer: Dilated fundus examination
Explanation: Dilated fundus examination assesses the vitreous, retina, choroid and optic disc and can identify posterior inflammation not visible on anterior-segment examination.

MCQ 13

Question:

A patient is being assessed at the first visit for suspected uveitis. The ophthalmologist wants to quantify current functional impairment and provide a baseline against which subsequent change can be judged. Which assessment is most appropriate?

Options:

Corneal diameter in both eyes
Palpebral aperture in both eyes
Lacrimal drainage in both eyes
Pupil diameter in both eyes
Visual acuity in both eyes
Correct Answer: Visual acuity in both eyes
Explanation: Recording visual acuity in each eye establishes the functional effect of uveitis and provides a baseline for detecting improvement or deterioration.

MCQ 14

Question:

A patient with non-infectious anterior uveitis shows marked improvement in anterior chamber inflammation after topical corticosteroid therapy. Which action of the treatment best explains this response?

Options:

Reduce inflammatory-cell activity and vascular leakage
Increase secretion of aqueous humor
Increase contraction of the iris sphincter
Enhance vitreous liquefaction and drainage
Increase retinal vascular permeability
Correct Answer: Reduce inflammatory-cell activity and vascular leakage
Explanation: Corticosteroids suppress intraocular inflammatory activity and reduce vascular permeability, thereby reducing inflammatory cells and protein leakage.

MCQ 15

Question:

A 58-year-old man develops a painful unilateral red eye shortly after a vesicular eruption affecting one side of his forehead. Slit-lamp examination confirms anterior uveal inflammation. Which infectious agent is most relevant?

Options:

Toxoplasma gondii
Treponema pallidum
Varicella-zoster virus
Mycobacterium tuberculosis
Adenovirus
Correct Answer: Varicella-zoster virus
Explanation: Varicella-zoster infection may cause anterior uveitis, particularly when ocular inflammation occurs in association with a unilateral dermatomal vesicular eruption.

MCQ 16

Question:

A patient has confirmed non-infectious posterior uveitis requiring corticosteroid treatment. The ophthalmologist is deciding the most appropriate route of anti-inflammatory therapy. Which factor should principally guide this decision?

Options:

Patient’s iris colour and refractive error
Presence of conjunctival pigmentation
Shape of the palpebral aperture
Severity and anatomical involvement
Presence of physiological anisocoria
Correct Answer: Severity and anatomical involvement
Explanation: In non-infectious posterior disease, the required route of corticosteroid therapy depends mainly on how severe the inflammation is and which ocular structures are involved.

MCQ 17

Question:

A patient has severe atypical posterior inflammation with progressive visual loss. Clinical findings strongly suggest infection, but routine systemic assessment has not identified the cause. Which additional diagnostic approach may be considered in this selected case?

Options:

Routine corneal pachymetry
Selected ocular fluid testing
Routine visual-field screening
Routine tear-film culture
Routine refraction testing
Correct Answer: Selected ocular fluid testing
Explanation: In severe or atypical cases with strong suspicion of infection, ocular fluid may be examined using specialized microbiological or molecular methods.

MCQ 18

Question:

A patient with recurrent ocular inflammation is subsequently diagnosed with a systemic inflammatory disorder requiring long-term treatment. Which management approach is most appropriate?

Options:

Treat only the systemic disorder
Treat only the ocular inflammation
Defer treatment until both eyes are involved
Use ocular lubricants as long-term therapy
Coordinate ophthalmic and systemic disease management
Correct Answer: Coordinate ophthalmic and systemic disease management
Explanation: When uveitis is associated with systemic inflammatory disease, control of both ocular and systemic inflammation requires coordinated specialist care.

MCQ 19

Question:

Slit-lamp examination of a patient with anterior uveitis reveals large greasy keratic precipitates. No systemic diagnosis has yet been established. Which interpretation of this finding is most appropriate?

Options:

A granulomatous pattern is suggested, but the cause is not established
Tuberculosis is confirmed by the ocular appearance alone
Sarcoidosis is confirmed by the ocular appearance alone
Herpetic infection is confirmed by the ocular appearance alone
Toxoplasmosis is confirmed by the ocular appearance alone
Correct Answer: A granulomatous pattern is suggested, but the cause is not established
Explanation: Large β€œmutton-fat” precipitates suggest granulomatous inflammation, but this pattern can occur with different diseases and does not establish a specific etiology by itself.

MCQ 20

Question:

During discussion of a patient with widespread uveal inflammation, a student is asked to identify the structures forming the vascular middle coat of the eye. Which group is anatomically correct?

Options:

Cornea, sclera and conjunctiva
Retina, optic nerve and macula
Iris, ciliary body and choroid
Lens, vitreous and retina
Cornea, iris and lens
Correct Answer: Iris, ciliary body and choroid
Explanation: The uveal tract is the vascular middle coat of the eye and consists anatomically of the iris, ciliary body and choroid.
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