Course Content
Multi-System Module — 3rd Year MBBS

📘Step 1. Curriculum Coverage

🔬 Pathology

 

Molecular Basis of Cancer

  • Describe the molecular/genetic basis of carcinogenesis.
  • Describe genetic lesions in cancer.
  • Define oncogene, proto-oncogene and oncoproteins.

Carcinogenesis

  • Enumerate carcinogens.
  • Describe the process of carcinogenesis.
  • Describe the hallmarks of cancer cells and process involved.
  • Describe the role of p53.

Chemical, Radiation and Microbial Carcinogenesis

  • Discuss properties of chemical carcinogens.
  • Describe direct and indirect chemical carcinogens and their mechanism of action.
  • Describe the mechanism of radiation carcinogenesis.
  • Enumerate viral and bacterial carcinogens.
  • Describe mechanism of carcinogenesis by viral and microbial oncogenes.

Medicine

  • Describe approach to manage a poisoned patient in accident and emergency department.

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