Course Content
Multi-System Module — 3rd Year MBBS

📘Step 1. Curriculum Coverage

💊 Pharmacology

 

Organophosphates and Cholinergic Toxicity

  • Enlist major organophosphate compounds.
  • Enlist the organophosphates used as “Nerve gases”.
  • Describe the clinical manifestations of organophosphate poisoning.
  • Explain the pharmacological rationale of prophylactic use of Pyridostigmine in situations where chemical warfare with nerve gases is anticipated.
  • Describe the drug treatment of organophosphate poisoning.
  • Enlist cholinesterase regenerating compounds.
  • Describe “aging” of the phosphorylated enzyme complex and its clinical importance regarding the management of organophosphate poisoning.

Mushroom Poisoning

  • Describe the clinical manifestations of mushroom poisoning.
  • Describe the drug treatment of mushroom poisoning.

⚖️ Forensic Medicine

 

Organophosphate Poisoning

  • Describe the mechanism of action of commonly used organophosphate poisons.
  • Describe the characteristic findings for organophosphate group in postmortem examination.
  • Describe different signs and symptoms for organophosphate group.
  • Describe the medico-legal importance for organophosphate group.
  • Explain fatal dose, fatal period, and treatment for organophosphate poisons.

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