📘Step 1. Curriculum Coverage
💊 Pharmacology
Drug Excretion and Clearance
- Define drug excretion and clearance.
- Enlist major and minor routes of drug excretion.
- Differentiate between excretion, elimination and clearance.
- Apply the formula for calculating drug clearance.
Maintenance Dose and Dose Calculation
- Define maintenance dose.
- Apply the formula for calculating maintenance dose.
- Apply Young’s, Dilling’s and Clark’s formulae for calculating drug doses.
Plasma Half-Life
- Define plasma half-life.
- Enlist drugs with short and long half-lives.
- Apply the formula for calculating plasma half-life.
- Explain its clinical significance.
Steady-State Concentration
- Define steady-state concentration.
- Describe the time required to reach steady state.
- Explain the importance of steady-state concentration in clinical practice.
First- and Zero-Order Kinetics
- Define first- and zero-order kinetics.
- Differentiate between first- and zero-order kinetics with examples.
Explain their clinical significance.
