Course Content
🧬 Theme I — Molecules and Bacteria
🧬 Theme II — Aging and Death
Foundation-II Module — 3rd Year MBBS

📘Step 1. Curriculum Coverage

🔬 Pathology

 

Foundations of Cell Injury

  • Define disease, etiology, pathogenesis, morphology, cell injury and homeostasis in the context of pathology.
  • Enumerate the different classes of pathology.
  • Describe the causes of cell injury ranging from gross physical trauma to single-gene defects.
  • Describe how the nature and severity of injury determine cellular responses.

Mechanisms of Cell Injury

  • Describe the general biochemical mechanisms of cell injury.
  • Describe ischemic and hypoxic cell injury.
  • Describe ischemia-reperfusion injury.
  • Describe free radical-induced cell injury.
  • Describe chemical cell injury.
  • Differentiate between reversible and irreversible cell injury.
  • Describe the mechanisms, morphological changes, biochemical changes and functional alterations associated with reversible and irreversible cell injury.

Subcellular Responses to Injury

  • Define phagocytosis, endocytosis, pinocytosis, autophagy and heterophagy.

Describe subcellular responses to injury, including lysosomal catabolism, heterophagy and autophagy.

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