Course Content
🧬 Theme I — Molecules and Bacteria
🧬 Theme II — Aging and Death
Foundation-II Module — 3rd Year MBBS

📘Step 1. Curriculum Coverage

🔬 Pathology

 

Cellular Adaptation

  • Describe the types of cellular adaptations.
  • Differentiate between physiological and pathological adaptation.
  • Define hypertrophy, hyperplasia, atrophy and metaplasia.
  • Describe the causes and mechanisms of hypertrophy, hyperplasia, atrophy and metaplasia.
  • Describe adaptive changes in clinical settings.
  • Describe hypertrophy of smooth endoplasmic reticulum with examples and mitochondrial alterations.
  • Describe cytoskeletal abnormalities in pathological states with examples.

Necrosis

  • Define necrosis.
  • Describe the types of necrosis with examples.
  • Describe the mechanisms and morphology of necrosis.

Apoptosis

  • Define apoptosis.
  • Describe physiological and pathological causes of apoptosis with examples.
  • Describe the morphological alterations associated with apoptosis.
  • Describe the biochemical features of apoptosis.
  • Describe the intrinsic and extrinsic pathways of apoptosis.
  • Differentiate between necrosis and apoptosis.
  • Describe the role of apoptosis in health and disease.

Cellular Ageing

  • Describe the mechanisms and causes of cellular ageing.
  • Explain genetic and environmental influences on cellular ageing.

Describe the structural and biochemical changes associated with cellular ageing.

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