Course Content
🧬 Theme I — Molecules and Bacteria
🧬 Theme II — Aging and Death
Foundation-II Module — 3rd Year MBBS

📘Step 1. Curriculum Coverage

🦠 Microbiology

 

Laboratory Diagnosis

  • Describe the bacteriological approach to diagnosis using blood, throat, stool, sputum, spinal fluid, urine, genital-tract and wound cultures.
  • Describe general principles of immunological and nucleic-acid-based methods used for identification of microorganisms.

Bacterial Pathogenesis

  • Define pathogen, infection, virulence, communicable disease, endemic, epidemic, pandemic, carrier, opportunist, commensal and colonizer.
  • Describe stages and determinants of bacterial pathogenesis.
  • Describe colonization, invasion, toxins and immune-pathogenesis.
  • Differentiate exotoxins and endotoxins.
  • Describe their modes of action as specified in the KMU curriculum.
  • Describe the four stages of a typical infectious disease.
  • Explain Koch’s postulates for establishing the causal role of an organism.

Antibacterial Vaccines

  • Define immunization and vaccination.
  • Describe active and passive acquired immunity in relation to immunization.
  • Enlist current bacterial vaccines and their indications.
  • Describe bacterial vaccines in terms of composition, preparation, indications, routes of administration and common side effects.

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