Course Content
Endocrine & Reproductive System Module β€” 4th Year MBBS
AIM EXAM ARENA

KMU Past Paper Practice

Topic 13 β€” Human Nutrition: Nutrients, Deficiency Disorders, Malnutrition and Obesity

4th Year MBBS β€’ 20 A-type Single Best Answer MCQs

MCQ 1

Question:

A nutritionist prepares identical daily menus for a healthy adult man and a woman who is breastfeeding. Although both menus contain the same food groups, the second woman requires adjustment of the quantities. Which principle best explains this difference?

Options:

All adults require identical nutrient quantities
Food variety determines requirements independently of physiology
Nutrient requirements vary with physiological state
Micronutrient requirements fall during lactation
Macronutrient requirements depend only on body height
Correct Answer: Nutrient requirements vary with physiological state
Explanation: Energy and nutrient needs change with growth, pregnancy, lactation and activity; a balanced diet must therefore be adapted to the individual.

MCQ 2

Question:

A university student consumes mainly refined bread, meat and sweetened beverages and develops persistent constipation. There is no gastrointestinal disease. Which dietary modification best addresses the nutritional problem?

Options:

Increase whole grains, vegetables and fruit
Increase refined carbohydrate intake
Replace vegetables with animal protein
Restrict dietary water intake
Increase saturated fat consumption
Correct Answer: Increase whole grains, vegetables and fruit
Explanation: Fibre-rich foods increase stool bulk and support normal gastrointestinal function; refined foods provide much less dietary fibre.

MCQ 3

Question:

A 70-kg healthy adult has a normal activity level and no condition that increases protein requirements. Which daily protein intake most closely matches the approximate requirement taught for healthy adults?

Options:

20 g/day
30 g/day
40 g/day
100 g/day
60 g/day
Correct Answer: 60 g/day
Explanation: At approximately 0.8–1.0 g/kg/day, a 70-kg healthy adult requires roughly 56–70 g of protein daily.

MCQ 4

Question:

A child has been maintained for months on an extremely low-fat diet. He develops poor growth and dry, scaly skin despite adequate carbohydrate and protein intake. Deficiency of which dietary component best explains the findings?

Options:

Branched-chain amino acids
Essential fatty acids
Simple carbohydrates
Dietary cholesterol
Soluble fibre
Correct Answer: Essential fatty acids
Explanation: Linoleic and alpha-linolenic acids are essential dietary fatty acids; severe deficiency may impair growth and cause dry, scaly skin.

MCQ 5

Question:

A young adult whose diet consists predominantly of polished rice develops progressive weakness and peripheral neurological symptoms. The deficient vitamin normally plays an important role in carbohydrate metabolism and neural function. Which vitamin is most likely deficient?

Options:

Vitamin B2
Vitamin B6
Vitamin B9
Vitamin B1
Vitamin C
Correct Answer: Vitamin B1
Explanation: Thiamine is required for normal carbohydrate metabolism and neural function; deficiency produces beriberi and neurological dysfunction.

MCQ 6

Question:

A patient with a chronically poor diet develops fissuring at the angles of the mouth, sore lips and a smooth inflamed tongue. Which nutritional deficiency best fits this pattern?

Options:

Riboflavin deficiency
Vitamin D deficiency
Vitamin K deficiency
Iodine deficiency
Selenium deficiency
Correct Answer: Riboflavin deficiency
Explanation: Riboflavin deficiency characteristically causes cheilosis, angular stomatitis and glossitis due to impaired flavin-dependent metabolic reactions.

MCQ 7

Question:

A nutritionally deprived patient develops dermatitis, peripheral sensory symptoms and anemia. Deficiency of a vitamin involved in amino-acid metabolism, neurotransmitter synthesis and heme formation is suspected. Which vitamin is involved?

Options:

Vitamin B2
Vitamin B3
Vitamin B6
Vitamin B7
Vitamin B9
Correct Answer: Vitamin B6
Explanation: Pyridoxine participates in amino-acid metabolism, neurotransmitter formation and heme synthesis; deficiency can cause dermatitis, neuropathy and anemia.

MCQ 8

Question:

A woman planning pregnancy receives nutritional counselling. Adequate intake of one vitamin is emphasized because deficiency during early fetal development increases the risk of neural tube defects. Which vitamin is most relevant?

Options:

Thiamine
Riboflavin
Niacin
Biotin
Folate
Correct Answer: Folate
Explanation: Folate is essential for DNA synthesis and rapid cell division; inadequate maternal folate increases the risk of fetal neural tube defects.

MCQ 9

Question:

A patient with severe nutritional deficiency develops peripheral neuropathy and evidence of increased red-cell membrane fragility. Deficiency of which vitamin, whose major function is antioxidant protection of cell membranes, is most likely?

Options:

Vitamin A
Vitamin E
Vitamin K
Vitamin B1
Vitamin C
Correct Answer: Vitamin E
Explanation: Vitamin E protects lipid membranes against oxidative injury; severe deficiency can produce neuropathy, myopathy and hemolytic changes.

MCQ 10

Question:

A community nutrition worker counsels families whose main iron sources are plant foods. Which meal combination would best improve utilization of the iron already present in the diet?

Options:

Pulses with a phytate-rich cereal only
Leafy vegetables with additional refined sugar
Whole grains with added saturated fat
Pulses with a vitamin C-rich fruit
Vegetables with reduced water intake
Correct Answer: Pulses with a vitamin C-rich fruit
Explanation: Vitamin C improves absorption of non-heme iron from plant foods, whereas phytates can reduce mineral bioavailability.

MCQ 11

Question:

A patient with prolonged severe dietary restriction develops anemia together with neutropenia and skeletal abnormalities. Deficiency of which trace element best explains this combination?

Options:

Iodine
Copper
Sodium
Potassium
Phosphorus
Correct Answer: Copper
Explanation: Copper supports iron metabolism and enzyme systems; severe deficiency may cause anemia, neutropenia and skeletal abnormalities.

MCQ 12

Question:

A child has adequate food available at home but progressively loses weight during a prolonged systemic illness that reduces appetite and increases metabolic requirements. How should this form of undernutrition be classified?

Options:

Primary overnutrition
Primary undernutrition
Isolated micronutrient excess
Constitutional short stature
Secondary undernutrition
Correct Answer: Secondary undernutrition
Explanation: Secondary undernutrition results from disease that reduces intake or utilization or increases nutrient requirements despite food availability.

MCQ 13

Question:

During rapid community screening, health workers need a simple anthropometric measure that reflects muscle and subcutaneous tissue reserve in young children and can help identify acute malnutrition. Which measurement is most useful?

Options:

Mid-upper-arm circumference
Head circumference
Chest circumference
Waist circumference
Hip circumference
Correct Answer: Mid-upper-arm circumference
Explanation: Mid-upper-arm circumference is a practical rapid measure of muscle and subcutaneous tissue reserve used in assessment of acute childhood malnutrition.

MCQ 14

Question:

A child’s anthropometric measurement is compared with a reference population and lies below βˆ’3 Z-scores for the relevant nutritional indicator. Which interpretation is most appropriate?

Options:

Normal nutritional variation
Mild nutritional abnormality only
Evidence of nutritional excess
Severe nutritional abnormality
Normal variation due to age
Correct Answer: Severe nutritional abnormality
Explanation: In WHO growth assessment, values below βˆ’2 Z-scores indicate abnormal undernutrition, while values below βˆ’3 indicate severe abnormality.

MCQ 15

Question:

A national nutrition survey identifies stunted children, adults with obesity and widespread micronutrient deficiencies within the same communities. Which public-health concept best describes this pattern?

Options:

Dietary uniformity
Protein complementation
Double burden of malnutrition
Nutritional rehabilitation
Isolated overnutrition
Correct Answer: Double burden of malnutrition
Explanation: The double burden describes coexistence of undernutrition or micronutrient deficiency with overweight and obesity in the same population.

MCQ 16

Question:

An adult gains considerable weight after beginning a long-term medicine. Dietary intake and activity also contribute, and no major endocrine disorder is found. How should the medicine be interpreted in the development of obesity?

Options:

It may act as one contributing determinant
It excludes dietary factors as a cause
It confirms an underlying endocrine disease
It prevents adipose tissue accumulation
It makes physical activity irrelevant
Correct Answer: It may act as one contributing determinant
Explanation: Obesity is multifactorial; some medicines promote weight gain but generally interact with dietary, behavioral, genetic and environmental determinants.

MCQ 17

Question:

A 46-year-old patient with longstanding obesity has mildly elevated liver enzymes. Imaging shows excess fat within the liver without another obvious nutritional explanation. Which obesity-associated complication is most likely?

Options:

Scurvy
Kwashiorkor
Rickets
Iron-deficiency anemia
Metabolic fatty liver disease
Correct Answer: Metabolic fatty liver disease
Explanation: Excess adiposity and insulin resistance promote hepatic triglyceride accumulation, making metabolic fatty liver an important complication of obesity.

MCQ 18

Question:

A 52-year-old woman with longstanding obesity develops progressive knee pain that worsens on walking. Examination suggests degenerative joint disease. Which mechanism most directly links her nutritional condition with this complication?

Options:

Reduced intestinal calcium absorption
Increased mechanical loading of joints
Reduced collagen synthesis from vitamin deficiency
Loss of skeletal muscle from protein deficiency
Impaired thyroid-hormone synthesis
Correct Answer: Increased mechanical loading of joints
Explanation: Excess body weight increases chronic mechanical stress on weight-bearing joints, contributing to osteoarthritis and mobility limitation.

MCQ 19

Question:

A 30-year-old woman with obesity reports increasingly irregular menstrual cycles and difficulty conceiving. No separate structural cause is identified. Which category of obesity-related complication best explains the presentation?

Options:

Respiratory complication
Hepatobiliary complication
Musculoskeletal complication
Reproductive complication
Micronutrient complication
Correct Answer: Reproductive complication
Explanation: Obesity can disturb reproductive function and is associated with menstrual irregularity and impaired fertility in susceptible women.

MCQ 20

Question:

A patient has severe obesity with significant obesity-related health problems despite structured lifestyle management. The clinical team considers escalation of treatment. Which principle is most appropriate regarding metabolic or bariatric surgery?

Options:

It replaces assessment of associated disease
It is the initial intervention for minor weight gain
It may be considered in selected patients with severe obesity
It removes the need for long-term follow-up
It is used primarily to correct micronutrient deficiency
Correct Answer: It may be considered in selected patients with severe obesity
Explanation: Metabolic or bariatric surgery is an escalation option for appropriately selected patients with severe obesity and requires specialist assessment and continued follow-up.
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