📘Step 1. Curriculum Coverage
💊 Pharmacology
Macrolides
- Enlist macrolides.
- Describe their antimicrobial spectrum.
- Describe their pharmacokinetics.
- Describe their mechanism of action.
- Describe the principal mechanism of resistance to macrolides.
- Describe their clinical uses.
- Describe their adverse effects.
- Describe their drug interactions.
- Differentiate erythromycin, clarithromycin and azithromycin with respect to dosing and clinical use.
- Relate the pharmacokinetics and pharmacodynamics of macrolides to their clinical applications and uses.
Linezolid
- Describe the mechanism of action of linezolid.
- Describe its clinical uses, with special emphasis on MRSA and vancomycin-resistant enterococci.
Clindamycin
- Describe the mechanism of action of clindamycin.
- Enumerate its clinical uses.
- Describe antibiotic-associated pseudomembranous colitis.
Streptogramins
- Enumerate streptogramins.
- Describe the clinical use of quinupristin-dalfopristin in vancomycin-resistant enterococci.
Chloramphenicol
- Describe the antimicrobial spectrum of chloramphenicol.
- Describe its mechanism of action.
- Enlist its clinical uses.
- Describe the reason for obsolescence of its systemic use.
- Enlist its adverse effects.
- Describe Gray Baby syndrome.
