Course Content
🫁 Theme I — Pain and Fatigue
🫁 Theme II — Trauma and Repair
Infection & Inflammation (Foundation II) Module — 3rd Year MBBS

📘Step 1. Curriculum Coverage

💊 Pharmacology

 

Macrolides

  • Enlist macrolides.
  • Describe their antimicrobial spectrum.
  • Describe their pharmacokinetics.
  • Describe their mechanism of action.
  • Describe the principal mechanism of resistance to macrolides.
  • Describe their clinical uses.
  • Describe their adverse effects.
  • Describe their drug interactions.
  • Differentiate erythromycin, clarithromycin and azithromycin with respect to dosing and clinical use.
  • Relate the pharmacokinetics and pharmacodynamics of macrolides to their clinical applications and uses.

Linezolid

  • Describe the mechanism of action of linezolid.
  • Describe its clinical uses, with special emphasis on MRSA and vancomycin-resistant enterococci.

Clindamycin

  • Describe the mechanism of action of clindamycin.
  • Enumerate its clinical uses.
  • Describe antibiotic-associated pseudomembranous colitis.

Streptogramins

  • Enumerate streptogramins.
  • Describe the clinical use of quinupristin-dalfopristin in vancomycin-resistant enterococci.

Chloramphenicol

  • Describe the antimicrobial spectrum of chloramphenicol.
  • Describe its mechanism of action.
  • Enlist its clinical uses.
  • Describe the reason for obsolescence of its systemic use.
  • Enlist its adverse effects.
  • Describe Gray Baby syndrome.

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