Course Content
🫁 Theme I — Pain and Fatigue
🫁 Theme II — Trauma and Repair
Infection & Inflammation (Foundation II) Module — 3rd Year MBBS

📘Step 1. Curriculum Coverage

🔬 Pathology

 

Malarial Parasite

  • Describe the life cycle and important properties of the malarial parasite.
  • Relate the pathogenesis of malaria to its clinical features and laboratory work-up.

💊 Pharmacology

 

Antimalarial Drugs

  • Describe chemoprophylaxis, causal prophylaxis, terminal prophylaxis and radical cure, with examples of drugs.
  • Classify antimalarial drugs.
  • Enlist drugs used for chemoprophylaxis of malaria.
  • Enlist drugs used for radical cure of malaria.
  • Describe the pharmacokinetics of chloroquine, with special emphasis on volume of distribution and dosing.
  • Describe the mechanisms of action of chloroquine, quinine, mefloquine, halofantrine, primaquine, pyrimethamine and artemisinins.
  • Describe the adverse effects of antimalarial drugs.
  • Describe cinchonism and blackwater fever.
  • Enlist antimalarial drugs relatively safe in pregnancy.
  • Describe antimalarial drugs contraindicated in G6PD deficiency.
  • Relate the pharmacokinetics and pharmacodynamics of antimalarial drugs to their clinical applications and uses.

🌍 Community Medicine

 

Epidemiology and Control of Malaria

  • Describe the epidemiological determinants, frequency and distribution of malaria.
  • Compare the prevalence/incidence of malaria in different provinces of Pakistan.
  • Explain preventive and control measures for malaria.
  • Describe the scope and functions of the malaria control program.

🩺 Family Medicine

 

Malaria in Family Practice

  • Explain the etiology, clinical features, types, investigations and management of malaria in family practice.
  • Describe red flags in a patient with malaria requiring referral to specialty care.
  • Identify at-risk patients for hepatitis and malaria and offer them screening.

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