Course Content
🔵 THEME 1 — Painful Swallowing
Focuses on anatomy, physiology, and disorders related to swallowing, including oral cavity, salivary glands, esophagus, and neural regulation of deglutition.
🔵 THEME 2 — Pain Epigastrium
Focus: Structural, functional, and clinical basis of epigastric pain. Includes abdominal wall, peritoneum, stomach, pancreas, gastric secretion, and peptic ulcer disease.
🔵 Theme 3 — Jaundice
🔵 Theme 4 — Diarrhoea and Constipation
🔵 Theme 5 — Bleeding Per Rectum
🔵 Theme 6 — Glucose Control (Carbohydrate Metabolism)
🔵 Theme 7 — Obesity (Fat Metabolism)
Gastrointestinal System (GIT) — Year 2 MBBS

📘 Step 1 — Curriculum Coverage

This topic uses the AIM Learning Cycle to help MBBS students understand mitochondrial energy generation and ATP production.

 

🔹 Biochemistry

 

  • Generation of proton gradient across inner mitochondrial membrane
    • Proton motive force
    • ATP synthesis by oxidative phosphorylation
  • Structure of ATP synthase (Complex V)
    • Rotary mechanism of ATP synthase
  • Control of respiration rate
    • Coupling between oxidation and phosphorylation
  • Respiratory chain inhibitors
    • Sites of action of respiratory inhibitors
  • Mechanism of uncouplers
    • Physiological role of uncouplers in heat production
  • Oxidation of reducing equivalents (NADH, FADH₂) via electron transport chain
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