Course Content
🔵 THEME 1 — Painful Swallowing
Focuses on anatomy, physiology, and disorders related to swallowing, including oral cavity, salivary glands, esophagus, and neural regulation of deglutition.
🔵 THEME 2 — Pain Epigastrium
Focus: Structural, functional, and clinical basis of epigastric pain. Includes abdominal wall, peritoneum, stomach, pancreas, gastric secretion, and peptic ulcer disease.
🔵 Theme 3 — Jaundice
🔵 Theme 4 — Diarrhoea and Constipation
🔵 Theme 5 — Bleeding Per Rectum
🔵 Theme 6 — Glucose Control (Carbohydrate Metabolism)
🔵 Theme 7 — Obesity (Fat Metabolism)
Gastrointestinal System (GIT) — Year 2 MBBS

📘 Step 1 — Curriculum Coverage

 

 

🔹 Biochemistry

 

Fatty Acid Synthesis

  • Organs where fatty acid synthesis occurs
    • Subcellular site of fatty acid synthesis
  • Source of acetyl CoA
    • Transport of acetyl CoA from mitochondria
  • Steps of fatty acid synthesis
    • Enzymes involved
  • Fatty acid synthase
    • Structure and components
  • Product of fatty acid synthase
    • Fate of fatty acid
  • Regulation of fatty acid synthesis
  • Why fatty acids cannot convert to glucose
  • Elongation of fatty acids
    • Desaturation of fatty acids
    • Regulation of elongation and desaturation

Fatty Acid Oxidation

  • Mobilization of fats from adipose tissue
  • Methods of fatty acid oxidation
  • Beta oxidation stages
  • Reactions of beta oxidation
  • ATP yield from palmitic acid
  • Oxidation of odd-chain fatty acids
  • Genetic deficiencies
  • MCAD deficiency
  • CAT deficiency
  • Comparison of fatty acid synthesis vs oxidation
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