Course Content
🔵 THEME 1 — Painful Swallowing
Focuses on anatomy, physiology, and disorders related to swallowing, including oral cavity, salivary glands, esophagus, and neural regulation of deglutition.
🔵 THEME 2 — Pain Epigastrium
Focus: Structural, functional, and clinical basis of epigastric pain. Includes abdominal wall, peritoneum, stomach, pancreas, gastric secretion, and peptic ulcer disease.
🔵 Theme 3 — Jaundice
🔵 Theme 4 — Diarrhoea and Constipation
🔵 Theme 5 — Bleeding Per Rectum
🔵 Theme 6 — Glucose Control (Carbohydrate Metabolism)
🔵 Theme 7 — Obesity (Fat Metabolism)
Gastrointestinal System (GIT) — Year 2 MBBS

📘 Step 1 — Curriculum Coverage

This topic integrates ketone metabolism and complex lipid synthesis pathways.

 

🔹 Biochemistry

 

Ketone Body Metabolism

  • Ketone bodies
    • Definition of ketogenesis
  • Steps of ketogenesis
  • Energy yield during ketogenesis
  • Conditions causing increased ketogenesis
  • Utilization of ketone bodies
  • Energy yield of ketone utilization
  • Regulation of ketogenesis
  • Ketoacidosis in diabetes

Complex Lipid Metabolism

  • Synthesis of triacylglycerol
  • Synthesis of phosphatidic acid
  • Substances formed from phosphatidic acid
  • Synthesis of glycerophospholipids
  • Degradation of glycerophospholipids
  • Synthesis of ceramide
  • Synthesis of sphingomyelin
  • Degradation of sphingomyelin
  • Niemann-Pick disease
  • Farber disease
  • Synthesis of glycosphingolipids
  • Degradation of glycosphingolipids
  • Abnormalities of phospholipid metabolism

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