📘 Step 1 — Curriculum Coverage
This topic integrates ketone metabolism and complex lipid synthesis pathways.
🔹 Biochemistry
Ketone Body Metabolism
- Ketone bodies
• Definition of ketogenesis - Steps of ketogenesis
- Energy yield during ketogenesis
- Conditions causing increased ketogenesis
- Utilization of ketone bodies
- Energy yield of ketone utilization
- Regulation of ketogenesis
- Ketoacidosis in diabetes
Complex Lipid Metabolism
- Synthesis of triacylglycerol
- Synthesis of phosphatidic acid
- Substances formed from phosphatidic acid
- Synthesis of glycerophospholipids
- Degradation of glycerophospholipids
- Synthesis of ceramide
- Synthesis of sphingomyelin
- Degradation of sphingomyelin
- Niemann-Pick disease
- Farber disease
- Synthesis of glycosphingolipids
- Degradation of glycosphingolipids
- Abnormalities of phospholipid metabolism
