Course Content
🔵 THEME 1 — Painful Swallowing
Focuses on anatomy, physiology, and disorders related to swallowing, including oral cavity, salivary glands, esophagus, and neural regulation of deglutition.
🔵 THEME 2 — Pain Epigastrium
Focus: Structural, functional, and clinical basis of epigastric pain. Includes abdominal wall, peritoneum, stomach, pancreas, gastric secretion, and peptic ulcer disease.
🔵 Theme 3 — Jaundice
🔵 Theme 4 — Diarrhoea and Constipation
🔵 Theme 5 — Bleeding Per Rectum
🔵 Theme 6 — Glucose Control (Carbohydrate Metabolism)
🔵 Theme 7 — Obesity (Fat Metabolism)
Gastrointestinal System (GIT) — Year 2 MBBS

📘 Step 1 — Curriculum Coverage

This topic establishes the foundation of nitrogen metabolism, linking amino acid breakdown to urea formation.

🔹 Biochemistry

 

Amino Acid Pool

  • Formation of amino acid pool
    • Sources of amino acids entering the pool
    • Utilization of amino acids from pool

Protein Catabolism Processes

  • Transamination
    • Deamination
    • Transdeamination
  • Clinical importance of transaminases

Ammonia Formation and Transport

  • Formation of ammonia in tissues
    • Transport of ammonia to liver
  • Ammonia toxicity
    • Effects of ammonia toxicity on brain

Urea Cycle

  • Krebs-Henseleit urea cycle
  • Steps of urea formation
  • Enzymes involved in urea cycle
  • Clinical significance of urea cycle enzyme defects

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